155694-97-6Relevant academic research and scientific papers
Improved procedures for the preparation of (+) - (1R, 2S, 4R)-4-amino-2-hydroxy-1-hydroxymethyl cyclopentane
Bray, Brian L.,Dolan, Simon C.,Halter, Bernard,Lackey, J. William,Schilling, Mark B.,Tapolczay, David J.
, p. 4483 - 4486 (1995)
Two methods for the stereospecific synthesis of the title compound are described. These short and efficient syntheses provide rapid access to this key intermediate in the construction of 2′-Deoxy Carbocyclic Nucleosides.
Chemical process for preparing an optically active aminodiol
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, (2008/06/13)
A process is claimed for preparing [1S(1(α, 2β, 4β)]-4-amino-2-hydroxymethyl -1-cyclopentanol from cis-4-((R)-benzoylamino)-2-cyclopentenecarboxylic acid, methyl ester in five steps. The invention also describes a number of novel intermediates useful in t
