Improved procedures for the preparation of (+) - (1R, 2S, 4R)-4-amino-2-hydroxy-1-hydroxymethyl cyclopentane

DOI: 10.1016/0040-4039(95)00764-4

Source and publish data:

Tetrahedron Letters p. 4483 - 4486 (1995)

Update date:2022-08-05

Topics:

Authors:

Bray, Brian L.

Dolan, Simon C.

Halter, Bernard

Lackey, J. William

Schilling, Mark B.

Tapolczay, David J.

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Article abstract of DOI:10.1016/0040-4039(95)00764-4

Two methods for the stereospecific synthesis of the title compound are described. These short and efficient syntheses provide rapid access to this key intermediate in the construction of 2′-Deoxy Carbocyclic Nucleosides.

Full text of DOI:10.1016/0040-4039(95)00764-4

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Product name:(S)-4-(Benzoylamino)-1-cyclopentene carboxylic acid methyl ester

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