155748-65-5

Basic information

• Product Name: methyl (2R,3S)-2-hydroxy-4-c-hexyl-3-<(S)-1-methylbenzylamino>butanoate
• Synonyms: methyl (2R,3S)-2-hydroxy-4-c-hexyl-3-<(S)-1-methylbenzylamino>butanoate
• CAS NO: 155748-65-5
• Molecular Weight: 319.444
• Mol File: 155748-65-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (2R,3S)-2-hydroxy-4-c-hexyl-3-<(S)-1-methylbenzylamino>butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2R,3S)-2-hydroxy-4-c-hexyl-3-<(S)-1-methylbenzylamino>butanoate(155748-65-5)
• EPA Substance Registry System: methyl (2R,3S)-2-hydroxy-4-c-hexyl-3-<(S)-1-methylbenzylamino>butanoate(155748-65-5)

Safety Data

• Hazardous Substances Data: 155748-65-5(Hazardous Substances Data)

Upstream product

• 129397-36-0 N-(2-cyclohexylethylidene)-(S)-α-methylbenzylamine 
• 146937-41-9 2-{[(E)-2-(tert-Butyl-dimethyl-silanyloxy)-1-methoxy-vinyloxy]-dimethyl-silanyl}-2-methyl-propane 

Downstream Products

• 121506-22-7 (2R,3S)-nor-C-statine hydrochloride 

Relevant articles and documents

Asymmetric synthesis of β-amino-α-hydroxy acids through Lewis acid-mediated addition of ketene acetal to imines

Asymmetric synthesis of β-amino-α-hydroxy acids, key components of medicinally important molecules including Paclitaxel, KRI-1314, amastatin, and microginin, has been attained from the aldimine coupling of chiral imines N-alkylidene-(S)- or (R)-α-methylbenzylamine with (Z)-α-methoxyketene methyltrimethylsilyl acetal, followed by demethylation, hydrogenolysis, and hydrolysis.