155789-92-7

Basic information

• Product Name: 3-Methoxy-2-Nitro-4-Picoline
• Synonyms: 3-Methoxy-2-Nitro-4-Picoline;3-Methoxy-4-Methyl-2-nitropyridine
• CAS NO: 155789-92-7
• Molecular Formula: C7H8N2O3
• Molecular Weight: 168.15002
• Product Categories: Pyridine
• Mol File: 155789-92-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 324.645 °C at 760 mmHg
• Flash Point: 150.14 °C
• Appearance: /
• Density: 1.248 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: 2-8°C
• PKA: -5.48±0.10(Predicted)
• CAS DataBase Reference: 3-Methoxy-2-Nitro-4-Picoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxy-2-Nitro-4-Picoline(155789-92-7)
• EPA Substance Registry System: 3-Methoxy-2-Nitro-4-Picoline(155789-92-7)

Safety Data

• Hazardous Substances Data: 155789-92-7(Hazardous Substances Data)

Usage

Uses

3-Methoxy-4-methyl-2-nitropyridine is used in the synthetic preparation of many useful biological compounds such as non-nucleoside inhibitors of HIV-1 reverse transcriptase.

InChI:InChI=1/C7H8N2O3/c1-5-3-4-8-7(9(10)11)6(5)12-2/h3-4H,1-2H3

Upstream product

• 1121-19-3 4-methylpyridin-3-ol 
• 15128-89-9 2-nitro-3-hydroxy-4-methylpyridine 
• 74-88-4 methyl iodide 

Downstream Products

• 155789-82-5 2-amino-1,7-dimethylimidazo<4,5-b>pyridine 
• 155790-05-9 4,N³-Dimethyl-pyridine-2,3-diamine 

Relevant articles and documents

Drug efflux pump inhibitor

A medicament for preventive and/or therapeutic treatment of a microbial infection which comprises as an active ingredient a compound represented by the following general formula (I): wherein, R1 and R2 represent hydrogen atom, a halogen atom, hydroxyl group or the like, W1 represents —CH═CH—, —CH2O—, —CH2CH2— or the like; R3 represents hydrogen atom, a halogen atom, hydroxyl group or an amino group; R4 represents hydrogen atom, a group of —OZ0-4R5 (Z0-4 represents an alkylene group, a fluorine-substituted alkylene group or a single bond, and R5 represents a cyclic alkyl group, an aryl group or the like); W2 represents a single bond or —C(R8)═C(R9)— (R8 and R9 represent hydrogen atom, a halogen atom, a lower alkyl group or the like, Q represents an acidic group, but W2 and Q may together form vinylidenethiazolidinedione or an equivalent heterocyclic ring; m and n represent an integer of 0 to 2, and q represents an integer of 0 to 3.