3-Methoxy-4-methyl-2-nitropyridine

Base Information

Chemical Name:3-Methoxy-4-methyl-2-nitropyridine
CAS No.:155789-92-7
Molecular Formula:C₇H₈N₂O₃
Molecular Weight:168.152
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20565601
Wikidata:Q82450792
Mol file:155789-92-7.mol

Synonyms:3-methoxy-4-methyl-2-nitropyridine;155789-92-7;3-Methoxy-2-nitro-4-picoline;SCHEMBL5908245;DTXSID20565601;LNAFAKGSYGVWPV-UHFFFAOYSA-N;3-methoxy-4-methyl-2-nitro-pyridine;AKOS006326464;SB54375;CS-0447269;A809680

Suppliers and Price of 3-Methoxy-4-methyl-2-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methoxy-4-methyl-2-nitropyridine
100mg
$ 120.00

Crysdot
3-Methoxy-4-methyl-2-nitropyridine 95+%
1g
$ 455.00

Chemcia Scientific
3-Methoxy-4-methyl-2-nitro-pyridine 95%
2.5 G
$ 900.00

American Custom Chemicals Corporation
3-METHOXY-2-NITRO-4-PICOLINE 95.00%
5G
$ 909.56

Alichem
3-Methoxy-4-methyl-2-nitropyridine
1g
$ 2837.10

Alichem
3-Methoxy-4-methyl-2-nitropyridine
500mg
$ 1769.25

Alichem
3-Methoxy-4-methyl-2-nitropyridine
250mg
$ 1058.40

Total 8 raw suppliers

Chemical Property of 3-Methoxy-4-methyl-2-nitropyridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.542
Boiling Point:324.645 °C at 760 mmHg
PKA:-5.48±0.10(Predicted)
Flash Point:150.14 °C
PSA：67.94000
Density:1.248 g/cm³
LogP:1.83000
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:168.05349212
Heavy Atom Count:12
Complexity:169

Purity/Quality:

97% ^*data from raw suppliers

3-Methoxy-4-methyl-2-nitropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=NC=C1)[N+](=O)[O-])OC
Uses 3-Methoxy-4-methyl-2-nitropyridine is used in the synthetic preparation of many useful biological compounds such as non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Technology Process of 3-Methoxy-4-methyl-2-nitropyridine

There total 3 articles about 3-Methoxy-4-methyl-2-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 15128-89-9
2-nitro-3-hydroxy-4-methylpyridine

: 74-88-4
methyl iodide

: 155789-92-7
3-methoxy-4-methyl-2-nitropyridine

Guidance literature:: With potassium carbonate; In acetone; at 100 ℃;

Reference yield:

: 1121-19-3
4-methylpyridin-3-ol

: 155789-92-7
3-methoxy-4-methyl-2-nitropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / conc. H₂SO₄, fuming HNO₃ / 2 h / 20 °C

2: 48 percent / K₂CO₃ / acetone / 100 °C

With sulfuric acid; nitric acid; potassium carbonate; In acetone;