15579-00-7 Usage
Description
3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID, also known as Aminoethyl-SS-propionic acid, is a cleavable compound that features a terminal amine and carboxylic acid group. It is characterized by its disulfide bonds, which can be cleaved using Dithiothreitol (DTT) reagent. 3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is a white solid and is known for its ability to react with various chemical groups, making it a versatile molecule in the field of biochemistry.
Uses
Used in Biochemistry and Molecular Biology:
3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is used as a reversible immobilization or crosslinking reagent for various applications in biochemistry and molecular biology. The terminal amine can react with carboxylic acid, activated NHS esters, and other carbonyl compounds, while the terminal carboxylic acid can form a stable amide bond with primary amines in the presence of activators such as EDC and HATU. This reagent is particularly useful for the study of protein-protein interactions, enzyme immobilization, and the development of biosensors.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is used as a key component in the development of drug delivery systems. Its ability to form stable amide bonds and react with various chemical groups makes it an ideal candidate for the design of targeted drug delivery systems, which can improve the efficacy and bioavailability of therapeutic agents.
Used in Materials Science:
3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is also utilized in materials science for the development of novel biocompatible materials. Its chemical properties allow for the creation of materials with specific interactions and functionalities, which can be applied in areas such as tissue engineering, biosensors, and drug delivery devices.
Check Digit Verification of cas no
The CAS Registry Mumber 15579-00-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,5,7 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15579-00:
(7*1)+(6*5)+(5*5)+(4*7)+(3*9)+(2*0)+(1*0)=117
117 % 10 = 7
So 15579-00-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H11NO2S2/c6-2-4-10-9-3-1-5(7)8/h1-4,6H2,(H,7,8)
15579-00-7Relevant articles and documents
DOLASTATIN 10 ANALOG
-
Page/Page column 47; 49, (2021/05/07)
Provided herein is a dolastatin 10 analog, useful for preparing conjugates thereof with targeting, diagnostic, imaging and other moieties. Also provided are the conjugates and uses thereof.
Based on the response of the GSH treatment integrated organic molecular probe and its preparation method (by machine translation)
-
Paragraph 0085; 0086; 0087; 0088, (2017/06/13)
The invention discloses a treatment based on GSH response of the integrated organic molecular probe and its preparation method, constructing a type based on near-infrared fluorescent dye and tumor micro environment for diagnosis and treatment of integrated molecular Image probe, GSH can be cut off by oxidation-reduction function of the disulfide bond in the probe, the release of the active drug, the drug can be monitored with the purpose of the transmission of the release. The invention synthetic process is relatively simple and rapid, active drug release fast, role cycle is short, small side effect on normal cell, has huge application potential, simple reaction steps, the operation procedure is clear, and the molecular Image probe with anticancer prodrug combination, by the reasonable designed structure, is able to realize tumor target detection, can also realize the effect of targeting for the treatment of tumor, while at the same time monitoring prodrugs in vivo biodistribution, and active release of the medicament and the enrichment process, to study the mechanism of action of drugs, tumor drug resistance mechanism is of great significance. (by machine translation)
TUNABLE FLUORESCENCE USING CLEAVABLE LINKERS
-
Paragraph 0066-0067, (2014/11/11)
The invention relates to cleavable chemistry in general, and in particular, to tunable fluoresence using cleavable linkers present in fluorochrome-quencher conjugates.
