1557968-11-2Relevant academic research and scientific papers
A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5- carboxamides
Zhao, Hai-Long,Zhou, Jie,Song, Hong-Rui,Xu, Bai-Ling
, p. 411 - 414 (2014)
A facile and efficient protocol was developed to access 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides through a three-component one-pot reaction, which involved potassium methyl cyanimidodithiocarbonate, 2-halo-N-arylacetamides and alcohols. The easy availability and the broad structural diversity of substrates make the reaction useful for the construction of libraries in drug discovery.
