1557968-63-4Relevant academic research and scientific papers
An eco-friendly water mediated synthesis of 1,2,3-triazolyl-2- aminopyrimidine hybrids as highly potent anti-bacterial agents
Nagarajan, Sangaraiah,Shanmugavelan, Poovan,Sathishkumar, Murugan,Selvi, Ramasamy,Ponnuswamy, Alagusundaram,Harikrishnan, Hariharan,Shanmugaiah, Vellasamy
supporting information, p. 419 - 422 (2014/03/21)
An elegant and efficient synthesis of novel 1,2,3-triazole fused 2-aminopyrimidine hybrids has been accomplished for the first time in the green solvent viz. water. The hybrid molecules exhibit significant anti-bacterial activity when screened against three human pathogens viz. Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumoniae. In comparison to the commercially marketed drug tetracycline, some of them are equally potent and a few are more potent.
