1558011-58-7

Basic information

• Product Name: 5-bromo-2-fluoro-N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]benzenesulfonamide
• CAS NO: 1558011-58-7
• Molecular Weight: 677.567
• Mol File: 1558011-58-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-fluoro-N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-fluoro-N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]benzenesulfonamide(1558011-58-7)
• EPA Substance Registry System: 5-bromo-2-fluoro-N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]benzenesulfonamide(1558011-58-7)

Safety Data

• Hazardous Substances Data: 1558011-58-7(Hazardous Substances Data)

Upstream product

• 960299-67-6 3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenylamine 
• 339370-40-0 5-bromo-2-fluorobenzene-1-sulfonyl chloride 
• 960299-66-5 4-(2-fluoro-4-nitrophenoxy)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline 

Downstream Products

• 1558011-51-0 2-fluoro-N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-5-(3-thienyl)benzenesulfonamide 

Relevant articles and documents

Discovery and biological evaluation of novel dual EGFR/c-Met inhibitors

Activating mutations in the epidermal growth factor receptor (EGFR) have been identified in a subset of non-small cell lung cancer (NSCLC), which is one of the leading cancer types worldwide. Application of EGFR tyrosine kinase inhibitors leads to acquire