155899-03-9Relevant academic research and scientific papers
Total synthesis of Taxol. 3. Formation of Taxol's ABC ring skeleton
Nicolaou,Yang,Liu,Nantermet,Claiborne,Renaud,Guy,Shibayama
, p. 645 - 652 (1995)
The synthesis of Taxol's ABC ring system has been achieved. The Shapiro coupling of an aldehydic C ring synthon (8) with an anionic A ring synthon derived from hydrazone 9 gave, diastereoselectively, A-B conjugate 10. Functional group manipulations and Mc
