Journal of the American Chemical Society p. 645 - 652 (1995)
Update date:2022-08-02
Topics:
Nicolaou
Yang
Liu
Nantermet
Claiborne
Renaud
Guy
Shibayama
The synthesis of Taxol's ABC ring system has been achieved. The Shapiro coupling of an aldehydic C ring synthon (8) with an anionic A ring synthon derived from hydrazone 9 gave, diastereoselectively, A-B conjugate 10. Functional group manipulations and Mc
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