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Boc-L-Cyclobutylglycine, also known as (S)-2-Aminocyclobutane-1-carboxylic acid, is a synthetic amino acid derivative that is widely utilized in the development of peptide-based drugs and pharmaceuticals. It is distinguished by the presence of a cyclobutyl group attached to the alpha carbon of the molecule, which endows it with unique steric and conformational properties. Boc-L-Cyclobutylglycine is frequently used as a building block in peptide synthesis and drug design, due to its capacity to influence the structure and function of peptides and proteins. The incorporation of Boc-L-Cyclobutylglycine into peptide sequences can alter the secondary structure and biological activity of the resulting molecules, making it an indispensable tool for drug discovery and development. As a vital component in the creation of innovative therapeutics, Boc-L-Cyclobutylglycine is instrumental in broadening the spectrum of pharmaceutical options available for the treatment of a variety of diseases and conditions.

155905-77-4

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155905-77-4 Usage

Uses

Used in Pharmaceutical Development:
Boc-L-Cyclobutylglycine is used as a building block in the synthesis of peptides and pharmaceuticals for its ability to modulate the structure and function of peptide-based drugs. Its unique cyclobutyl group attachment allows for the creation of molecules with distinct secondary structures and biological activities, enhancing the efficacy and specificity of therapeutic agents.
Used in Drug Discovery:
Boc-L-Cyclobutylglycine is utilized as a key component in drug discovery processes to explore novel therapeutic agents. Its incorporation into peptide sequences can lead to the development of new drugs with improved pharmacological properties, offering potential treatments for a range of diseases and conditions.
Used in Peptide Synthesis:
In the field of peptide synthesis, Boc-L-Cyclobutylglycine is employed as a crucial building block. Its unique properties allow for the design of peptides with specific conformational characteristics, which can be tailored for various biological targets and therapeutic applications.
Used in Conformational Studies:
Boc-L-Cyclobutylglycine is used in conformational studies to understand how the cyclobutyl group influences the secondary structure of peptides. This knowledge is vital for the rational design of peptides with desired properties, such as stability, solubility, and bioactivity.
Used in the Creation of Novel Therapeutics:
Boc-L-Cyclobutylglycine plays a critical role in the development of new therapeutic agents. Its unique structural features enable the design of peptides and proteins with enhanced biological activities, potentially leading to more effective treatments for various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 155905-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,9,0 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 155905-77:
(8*1)+(7*5)+(6*5)+(5*9)+(4*0)+(3*5)+(2*7)+(1*7)=154
154 % 10 = 4
So 155905-77-4 is a valid CAS Registry Number.

155905-77-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-2-((tert-Butoxycarbonyl)amino)-2-cyclobutylacetic acid

1.2 Other means of identification

Product number -
Other names Boc-L-Cyclobutylglycine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:155905-77-4 SDS

155905-77-4Downstream Products

155905-77-4Relevant academic research and scientific papers

A Versatile Method for the Synthesis of (S)- or (R)-Cycloalkylglycines, (S)- or (R)-N-Heterocyclic and α,β-Unsaturated N-Heterocyclic α-Amino Acids

Pauly, Regine,Sasaki, N. Andre,Potier, Pierre

, p. 237 - 240 (2007/10/02)

Two different types of cyclic α-amino acids, cycloalkylglycines and N-heterocyclic α-amino acids, were prepared in optically pure form from the same chiral synthon 1-(R) (or 1-(S)) simply by altering the quantity or type of base required for anion formation.Elaboration of the heterocyclic intermediate 3 provided α,β-unsaturated N-heterocyclic α-amino acids.

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