155967-58-1

Basic information

• Product Name: 4-(PYRIDIN-4-YLSULFANYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4-(PYRIDIN-4-YLSULFANYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-Butyl 4-(pyridin-4-ylthio)piperidine-1-carboxylate
• CAS NO: 155967-58-1
• Molecular Formula: C15H22N2O2S
• Molecular Weight: 294.41
• Mol File: 155967-58-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(PYRIDIN-4-YLSULFANYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(PYRIDIN-4-YLSULFANYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(155967-58-1)
• EPA Substance Registry System: 4-(PYRIDIN-4-YLSULFANYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(155967-58-1)

Safety Data

• Hazardous Substances Data: 155967-58-1(Hazardous Substances Data)

Usage

General Description

4-(Pyridin-4-ylsulfanyl)-piperidine-1-carboxylic acid tert-butyl ester is a chemical compound with the structure C16H24N2O2S. It is a tert-butyl ester derivative of a piperidine carboxylic acid that contains a pyridin-4-ylsulfanyl group. 4-(PYRIDIN-4-YLSULFANYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER may have potential applications in organic synthesis and pharmaceutical research, as piperidine derivatives are commonly used as building blocks in medicinal chemistry. The presence of the pyridin-4-ylsulfanyl group can impart specific reactivity and biological activity to the compound, making it of interest to researchers in the development of new drugs or materials. The tert-butyl ester moiety also provides stability and can be easily removed under mild conditions, making this compound a versatile reagent in chemical synthesis.

Upstream product

• 4556-23-4 pyridine-4-thiol 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Relevant articles and documents

Cyclic amine compounds as CCR5 antagonists

A compound of formula (I) (wherein R1is a hydrogen atom, a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, R2is a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, or R1and R2may combine to each other together with A to form a heterocyclic group which may be substituted; A is N or N+—R5.Y?(R5is a hydrocarbon group; Y?is a counter anion); R3is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; n is 0 or 1; R4is a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, an alkoxy group which may be substituted, an aryloxy group which may be substituted, or an amino group which may be substituted, E is a divalent aliphatic hydrocarbon group which may be substituted by group(s) other than oxo; G1is a bond, CO or SO2; G2is CO, SO2, NHCO, CONH or OCO; J is methine or a nitrogen atom; and each of Q and R is a bond or a divalent C1-3aliphatic hydrocarbon which may be substituted; provided that J is methine when G2is OCO, that one of Q and R is not a bond when the other is a bond and that each of Q and R is not substituted by oxo group(s) when G1is a bond) or a salt thereof has a potent CCR5 antagonistic activity and can be advantageously used for the treatment or prevention of infectious disease of various HIV in human (e.g. AIDS).