155997-58-3Relevant academic research and scientific papers
Lewis Acid-Promoted Selective Rearrangement of Trisubstituted Epoxides to Aldehydes or Ketones
Maruoka, Keiji,Murase, Noriaki,Bureau, Ronan,Ooi, Takashi,Yamamoto, Hisashi
, p. 3663 - 3672 (1994)
Rearrangement of trisubstituted epoxides has been effected under the influence of various Lewis acids.Among these, methylaluminum bis(4-bromo-2,6-di-tert-butylphenoxide) (MABR) can be selectively rearranged from trisubstituted epoxides to aldehydes, while
New metal-free one-pot synthesis of substituted allenes from enones
Tang, Meng,Fan, Chun-An,Zhang, Fu-Min,Tu, Yong-Qiang,Zhang, Wen-Xue,Wang, Ai-Xia
supporting information; experimental part, p. 5585 - 5588 (2009/06/18)
(Chemical Equation Presented) A new metal-free, one-pot synthesis of substituted allenes from enones was discovered for the first time, in which a tertiary amine as a base was found to be an effective promoter in such novel transformations. The present synthetic protocol proceeded readily with high compatibility of sensitive functional groups, and it provides a new efficient way to access a series of synthetically important allenes without the use of metallic reagents or catalysts.
