156021-02-2

Basic information

• Product Name: [1-(2,2-Dichloro-1-phenyl-cyclopropyl)-meth-(E)-ylidene]-thiophen-2-ylmethyl-amine
• CAS NO: 156021-02-2
• Molecular Weight: 310.247
• Mol File: 156021-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-(2,2-Dichloro-1-phenyl-cyclopropyl)-meth-(E)-ylidene]-thiophen-2-ylmethyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(2,2-Dichloro-1-phenyl-cyclopropyl)-meth-(E)-ylidene]-thiophen-2-ylmethyl-amine(156021-02-2)
• EPA Substance Registry System: [1-(2,2-Dichloro-1-phenyl-cyclopropyl)-meth-(E)-ylidene]-thiophen-2-ylmethyl-amine(156021-02-2)

Safety Data

• Hazardous Substances Data: 156021-02-2(Hazardous Substances Data)

Upstream product

• 27757-85-3 2-Aminomethylthiophene 
• 122801-51-8 2,2-dichloro-1-phenylcyclopropane-1-carbaldehyde 
• 80234-04-4 2-phenylacrylaldehyde diethyl acetal 
• 156020-80-3 2,2-dichloro-1-phenylcyclopropanecarbaldehyde diethyl acetal 

Downstream Products

• 78313-67-4 5-phenyl-2-(α-thienyl)pyridine 

Relevant articles and documents

Thermal Rearrangement of N-Arylmethyl- and N-Alkyl-2,2-dihalogenocyclopropyl Imines

An extended study of the thermal isomerization of 1-substituted 2,2-dihalogenocyclopropyl imines is reported.The thermolysis of N-arylmethyl-2,2-dichlorocyclopropanecarbaldimines 15a-h produces 2-aryl- 16a-h and 2-aryl-4-chloro-pyridine derivatives 17a-h, while N-cyclopropyl imines 15i, j yielded N-alyklchloropyrroles.The 2,2-dibromocyclopropane analogue undergoes thermolysis at lower temperatures.An ionic mechanism triggered by the halide ion dissociation is proposed for the thermal rearrangement on the basis of a study using deuterated imine 15m, and the effects of additives and solvents.On the other hand, difluorocyclopropyl imine undergoes a homolytic cleavage of cyclopropane 1,3-bond with lower activation energy than the dichlorocyclopropyl imine, and afforded the N-alykl-3-fluoropyrrole derivative preferentially.