80234-04-4

Basic information

• Product Name: Atropaldehydediethylacetal
• Synonyms: Atropaldehydediethylacetal;Benzene, [1-(diethoxyMethyl)ethenyl]-
• CAS NO: 80234-04-4
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight: 206.28082
• Mol File: 80234-04-4.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Atropaldehydediethylacetal(CAS DataBase Reference)
• NIST Chemistry Reference: Atropaldehydediethylacetal(80234-04-4)
• EPA Substance Registry System: Atropaldehydediethylacetal(80234-04-4)

Safety Data

• Hazardous Substances Data: 80234-04-4(Hazardous Substances Data)

Upstream product

• 6175-45-7 2,2-diethoxyacetophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 17592-40-4 2-bromo-3,3-diethoxypropene 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 10160-86-8 2,3-dibromo-1,1-diethoxypropane 
• 3054-95-3 acrylaldehyde diethyl acetal 
• 98-80-6 phenylboronic acid 
• 100-42-5 styrene 
• 2415-80-7 1,1-dichloro-2-phenylcyclopropane 
• 64-17-5 ethanol 
• 122-51-0 orthoformic acid triethyl ester 
• 112919-42-3 1-ethoxy-2-phenylcyclopropene 

Downstream Products

• 156020-80-3 2,2-dichloro-1-phenylcyclopropanecarbaldehyde diethyl acetal 
• 156020-82-5 2,2-dibromo-1-phenylcyclopropanecarbaldehyde diethylacetal 
• 87698-58-6 Ethyl 1-(3-ethoxy-2-phenyl-2-propenyl)-2-oxocyclopentanecarboxylate 
• 183961-07-1 3-carbamoyl-2-phenylpropionaldehyde 
• 183961-10-6 carbamic acid 3,3-diethoxy-2-phenyl-propyl ester 
• 15295-60-0 phenylpropionaldehyde diethyl acetal 
• 6175-45-7 2,2-diethoxyacetophenone 
• 351026-98-7 (4R)-(+)-cis-2-benzoyl-4-methyl-1,3-dioxane 
• 96248-16-7 3,3-Diaethoxy-2-phenyl-propanol-⁽¹⁾ 
• 4432-63-7 2-phenylacrolein 
• 87698-10-0 (E)-2-(3-Ethoxy-2-phenyl-2-propenyl)-2-methyl-1,3-cyclopentanedione 
• 87698-11-1 (Z)-2-(3-Ethoxy-2-phenyl-2-propenyl)-2-methyl-1,3-cyclopentanedione 
• 112919-41-2 (3,3-dimethoxyprop-1-en-2-yl)benzene 
• 20563-92-2 2-phenyl-acrylaldehyde-(2,4-dinitro-phenylhydrazone) 

Relevant articles and documents

Modular Synthesis of α-Substituted Alkenyl Acetals by a Palladium-Catalyzed Suzuki Reaction of α-Haloalkenyl Acetals with Organoboranes

A modular and straightforward synthetic strategy for the preparation of α-substituted alkenyl acetals has been developed. α-Haloalkenyl acetals react smoothly with (het)aryl boronic acids, aryl boronates, or B-Alkyl-9-borabicyclo[3.3.1]nonanes through Pd-catalyzed Suzuki cross-coupling under mild conditions with good to high yields. This protocol features a broad substrate scope and good functional-group compatibility, and is easily scaled up.

Catalytic Asymmetric Cycloadditions of Silyl Nitronates Bearing α-Aryl Group

1,3-Dipolar cycloadditions of 2-alkylacroleins or atropaldehyde with triisopropylsilyl nitronates bearing an α-aryl group produced 3-aryl-2-isoxazolines having a chiral quaternary center in up to 94% ee and up to 88% yield with the aid of Corey’s oxazaborolidine catalyst. Specifically, the TIPS nitronate with an α-(p-methoxyphenyl) group gave mainly the 2-isoxazolines having an all-carbon quaternary center.

AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES

Compositions and methods are disclosed for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1). The compounds disclosed are amine-containing and amide-containing compounds. The compounds and compositions are useful for treatment of diseases, including inflammation, inflammatory diseases and autoimmune disorders.