156049-34-2Relevant academic research and scientific papers
Copper-Catalyzed Dihydroquinolinone Synthesis from Isocyanides and O-Benzoyl Hydroxylamines
Yang, Zhen,Jiang, Kun,Chen, Ying-Chun,Wei, Ye
, p. 3725 - 3734 (2019/03/20)
A copper-catalyzed protocol has been realized for the rapid assembly of dihydroquinolinones from readily accessible isocyanides and O-benzoyl hydroxylamines. The reactions (10 mol % of CuOAc, 10 mol % of dppe, 3 equiv of PhONa, 30 °C) deliver various stru
Cobalt(II)-Catalyzed Isocyanide Insertion Reaction with Sulfonyl Azides in Alcohols: Synthesis of Sulfonyl Isoureas
Jiang, Tian,Gu, Zheng-Yang,Yin, Ling,Wang, Shun-Yi,Ji, Shun-Jun
supporting information, p. 7913 - 7919 (2017/08/14)
A Co(II)-catalyzed isocyanide insertion reaction with sulfonyl azides in alcohols to form sulfonyl isoureas via nitrene intermediate has been developed. This protocol provides a new, environmentally friendly, and simple strategy for the synthesis of sulfonyl isourea derivatives by employing a range of substrates under mild conditions.
Cross-Cycloaddition of Two Different Isocyanides: Chemoselective Heterodimerization and [3+2]-Cyclization of 1,4-Diazabutatriene
Hu, Zhongyan,Yuan, Haiyan,Men, Yang,Liu, Qun,Zhang, Jingping,Xu, Xianxiu
supporting information, p. 7077 - 7080 (2016/07/06)
A new cross-cycloaddition reaction between a wide range of isocyanides and 2-isocyanochalcones (or analogues) was developed for the expeditious synthesis of pyrrolo[3,4-b]indoles under thermal conditions. On the basis of the experimental results and DFT c
New route to the 5,12-dihydro-7H-benzo[2,3]azepino[4,5-b]indol-6-one core via a tin-mediated indole synthesis
Henry, Nicolas,Blu, Jerome,Beneteau, Valerie,Merour, Jean-Yves
, p. 3895 - 3901 (2008/02/09)
A new route to the paullone scaffold was designed. The key step consisted in a free radical indole formation from an o-alkenyl arylisonitrile followed by Stille coupling with N-Boc-o-iodoaniline. After deprotection and closure of the seven-membered ring by lactamisation, parent or cyano-substituted paullones were obtained in moderate to good yields. Georg Thieme Verlag Stuttgart.
Synthesis of 2,3-disubstituted indoles by palladium-mediated coupling of 2-iodoindoles
Tokuyama, Hidetoshi,Kaburagi, Yosuke,Chen, Xiaoqi,Fukuyama, Tohru
, p. 429 - 434 (2007/10/03)
N-Unprotected 2-iodoindoles are synthesized by treatment of 2- stannylindoles with iodine, which in turn are prepared by tin-mediated radical cyclization of 2-alkenylphenylisocyanides. Palladium-catalyzed coupling reactions of N-unprotected 2-iodoindoles
