156050-11-2Relevant academic research and scientific papers
Synthesis of cycloalkyl/steroidal heteroaryl sulfides using rhodium-catalyzed heteroaryl exchange reaction
Arisawa, Mieko,Nakai, Katsuya,Suzuki, Ren,Yamada, Tomoki,Yamaguchi, Masahiko
, p. 104 - 118 (2020/01/28)
Cycloalkyl heteroaryl sulfides are efficiently synthesized by the single-bond cleavage and exchange reaction of S-cycloalkyl thioesters and heteroaryl ethers without using a base. The method is applicable to steroids at the A- and D-rings, and provides diverse heteroarylthiolated steroids with five- and six-membered heteroarenes.
