156060-97-8

Basic information

• Product Name: 2-(2-fluorophenyl)-4,5-dihydro-1,3-oxazole
• Synonyms: 2-(2-fluorophenyl)-4,5-dihydro-1,3-oxazole
• CAS NO: 156060-97-8
• Molecular Weight: 165.167
• Mol File: 156060-97-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(2-fluorophenyl)-4,5-dihydro-1,3-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-fluorophenyl)-4,5-dihydro-1,3-oxazole(156060-97-8)
• EPA Substance Registry System: 2-(2-fluorophenyl)-4,5-dihydro-1,3-oxazole(156060-97-8)

Safety Data

• Hazardous Substances Data: 156060-97-8(Hazardous Substances Data)

Upstream product

• 393-52-2 2-Fluorobenzoyl chloride 
• 445-29-4 o-fluoro-benzoic acid 
• 111904-31-5 2-fluoro-N-(2-hydroxyethyl)benzamide 
• 394-47-8 2-fluorobenzonitrile 
• 141-43-5 ethanolamine 
• 79-37-8 oxalyl dichloride 
• 2576-47-8 2-bromoethylamine hydrobromide 

Downstream Products

• 178672-06-5 2-fluoro-1-oxazol-2-yl-benzene 
• 179117-13-6 2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-1,3-oxazole 
• 895167-37-0 (2-(2-(diphenylphosphino)phenyl)-4,5-dihydrooxazole)-(η4-1,5-cyclooctadiene)iridium(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate 
• 178672-07-6 4-benzyl-1-(2-oxazol-2-ylphenyl)piperazine 

Relevant articles and documents

Oxazolinyl-Assisted Ru(II)-Catalyzed C-H Allylation with Allyl Alcohols and Synthesis of 4-Methyleneisochroman-1-ones

We report herein a ruthenium-catalyzed, oxazoline-directed strategy for C-H allylation of aryl oxazolines using allylic alcohols as the coupling partner. The present transformation unravels the unusual reactivity of allylic alcohols in the synthesis of 4-

Synthesis and structural characterization of new phosphinooxazoline complexes of iron

The first phosphinooxazoline chelate complexes of iron were synthesized, and their structural and electronic properties were studied. The known phosphinooxazolines 2-(2-(diphenylphosphino)phenyl)-4,5-dihydrooxazole (7a), 2-(2-(diphenylphosphino)phenyl)-4,

Synthesis, microwave-assisted polymerization, and polymer properties of fluorinated 2-phenyl-2-oxazolines: A systematic study

We present a detailed systematic study of the synthesis and ability of fluorinated 2-phenyl-2-oxazolines to undergo polymerization. The synthesis of these compounds is based on a two-step procedure that gives the desired 2-oxazolines in moderate-to-good yields. All the compounds were fully characterized by IR and NMR (1H, 13C, and 19F) spectroscopy, mass spectrometry, and elemental analysis. The 2-oxazolines were subsequently used as monomers for living cationic ring-opening polymerization (CROP) with microwave irradiation as the heat source (T= 140°C), nitromethane as the solvent, and methyl tosylate as the initiator. The linear first-order kinetic plots of the polymerizations accompanied by a linear increase of the molecular weight with conversion and low polydispersity index (PDI) values (generally below 1.30) indicate a living polymerization mechanism. The resulting polymerization rates reflect a strong sensitivity to the quantity of fluorine substituents in general and the presence or absence of ortho-fluoro substituents of the phenyl ring in particular. All the polymers were isolated and characterized by size-exclusion chromatography and MALDI-TOF mass spectrometry. Finally, a detailed investigation of selected polymer properties was performed by using differential scanning calorimetry, thermogravimetric analysis, and contact-angle measurements, thus resulting in structure-property relationships. Whereas the thermal properties of the polymers are mostly influenced by the presence of ortho-fluoro substituents, the surface properties are mainly determined by the presence of para- and/or metafluoro substituents.