156083-36-2Relevant academic research and scientific papers
Synthesis of a protected (±)-calicheamicinone derivative by sequential introduction of functionality into the bicyclo[7.3.1]enediyne core structure
Magnus, Philip,Miknis, Gregory F.,Press, Neil J.,Grandjean, Didier,Taylor, G. Mark,Harling, John
, p. 6739 - 6748 (1997)
The core bicyclo[7.3.0]enediyne 3 has been synthesized from the protected cyclohexane-1,2-dione 6 and enediyne component 9. Conversion of 20 into more highly functionalized enediynes was accomplished by oxidation and amination to give 27. ProteCtion of 27
A general strategy using η2Co2(CO)6 acetylene complexes for the synthesis of the enediyne antitumor agents esperamicin, calicheamicin, dynemicin and neocarzinostatin
Magnus
, p. 1397 - 1418 (2007/10/02)
A review of the use of η2Co2(CO)6-acetylene complexes as stable intermediates for the construction of the core structures of the antitumor enediyne agent esperamicin, calicheamicin, dynemicin and neocarzinostatin from the
