156098-16-7Relevant academic research and scientific papers
One-pot synthesis of unsymmetrical diaryl thioethers by palladium-catalyzed coupling of two aryl bromides and a thiol surrogate
Fernandez-Rodriguez, Manuel A.,Hartwig, John F.
supporting information; experimental part, p. 2355 - 2359 (2010/07/02)
Extraordinarily simple, convenient, and efficient: A general and operationally simple one-pot synthesis of unsymmetrical diaryl sulfides by coupling two different bromoarenes and triisopropylsilanethiol (TIPS-SH) is reported. This protocol overcomes the narrow availability of arene thiols and their instability to oxidation. These reactions catalyzed by palladium complexes generated from the alkylbisphosphine CyPF-tBu occur in good to excellent yields with wide scope and high tolerance of functional groups.
A general and efficient method for the synthesis of silyl-protected arenethiols from aryl halides or triflates
Kreis, Michael,Braese, Stefan
, p. 313 - 319 (2007/10/03)
An improved palladium-catalyzed synthesis of silyl-protected arenethiols has been developed. This method is particularly useful because of its experimental simplicity, high generality and high level of functional group toleration. The first synthesis of enantiomerically pure [2.2]paracyclophane-4- thiol was realized employing this method.
Oxidation of aromatic and aliphatic triisopropylsilanylsulfanyls to sulfonyl chlorides: Preparation of sulfonamides
Gareau, Yves,Pellicelli, Jonathan,Laliberté, Sébastien,Gauvreau, Danny
, p. 7821 - 7824 (2007/10/03)
A series of aromatic and aliphatic triisopropylsilanylsulfanyls were prepared and oxidized to the sulfonyl chlorides with KNO3/SO 2Cl2. The sulfonyl chlorides were characterized via their conversion to sulfonamides.
POTASSIUM TRIISOPROPYLSILANETHIOLATE: VINYL AND ARYL SULFIDES THROUGH Pd-CATALYZED CROSS COUPLING
Rane, Anil M.,Miranda, Edgar I.,Soderquist, John A.
, p. 3225 - 3226 (2007/10/02)
Vinyl and aryl halides are efficiently converted, under Pd catalysis, with KSTIPS (1) to the corresponding silyl sulfides (2, 3).The naphthyl derivative was easily hydrolyzed to the mercaptan 4, or alkylated or alkenylated to provide unsymmetrical sulfides (5, 6).
