156126-53-3Relevant academic research and scientific papers
Expedient approach to chiral cyclobutanones: Asymmetric synthesis of cyclobut-G
Darses, Benjamin,Greene, Andrew E.,Coote, Susannah C.,Poisson, Jean-Francois
, p. 821 - 824 (2008)
An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.
