156137-99-4 Usage
Description
Rapacuronium bromide was introduced in the US as a parenterally
administered adjunct to general anesthesia during surgical procedures. It is a
new steroidal derivative belonging to the same class as vecuronium bromide.
This 2,16-bispiperidinylandrostane derivative can be synthesized in 3 steps from
the 3-hydroxy-androstan-17-one analog and finally quaternized with allyl
bromide. Rapacuronium bromide is a nondepolarizing neuromuscular blocking
drug with a rapid onset and a short duration of action. With a relatively low
potency (ED90 = 1.15 mg/kg), Rapacuronium is expected to be substituted for
the polarizing succinylcholine with very short duration of action.
Uses
Rapacuronium Bromide is an aminosteroidal nondepolarizing neuromuscular blocking agent and was used as a anesthesia.
Brand name
Raplon
Check Digit Verification of cas no
The CAS Registry Mumber 156137-99-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,1,3 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156137-99:
(8*1)+(7*5)+(6*6)+(5*1)+(4*3)+(3*7)+(2*9)+(1*9)=144
144 % 10 = 4
So 156137-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C37H61N2O4.BrH/c1-6-20-39(21-12-9-13-22-39)32-24-30-28-15-14-27-23-33(42-26(3)40)31(38-18-10-8-11-19-38)25-37(27,5)29(28)16-17-36(30,4)35(32)43-34(41)7-2;/h6,27-33,35H,1,7-25H2,2-5H3;1H/q+1;/p-1/t27-,28+,29-,30-,31-,32-,33-,35-,36-,37-;/m0./s1
156137-99-4Relevant articles and documents
Monoquaternary 2,16-bispiperidinylandrostane derivatives
-
, (2008/06/13)
Monoquaternary 2,16-bispiperidinylandrostane neuromuscular blocking derivatives having the formula: STR1 wherein R1 is ethyl; R2 is methyl or allyl; and X- is a pharmaceutically acceptable anion; or pharmaceutically acceptable salts thereof.
