156149-53-0

Basic information

• Product Name: Acetamide, N-[3-(acetyloxy)-2-(3,4-dimethoxyphenyl)-6,7-dimethoxy-1-naphthalenyl] -N-(phenylmethyl)-
• CAS NO: 156149-53-0
• Molecular Formula: C31H31NO7
• Molecular Weight: 529.59
• Mol File: 156149-53-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[3-(acetyloxy)-2-(3,4-dimethoxyphenyl)-6,7-dimethoxy-1-naphthalenyl] -N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[3-(acetyloxy)-2-(3,4-dimethoxyphenyl)-6,7-dimethoxy-1-naphthalenyl] -N-(phenylmethyl)-(156149-53-0)
• EPA Substance Registry System: Acetamide, N-[3-(acetyloxy)-2-(3,4-dimethoxyphenyl)-6,7-dimethoxy-1-naphthalenyl] -N-(phenylmethyl)-(156149-53-0)

Safety Data

• Hazardous Substances Data: 156149-53-0(Hazardous Substances Data)

Upstream product

• 26954-85-8 o-homoveratroylhomoveratric acid 
• 75-36-5 acetyl chloride 
• 100-46-9 benzylamine 
• 79781-25-2 methyl 2-<(3,4-dimethoxyphenyl)acetyl>-4,5-dimethoxyphenylacetate 

Relevant articles and documents

A convenient approach to the synthesis of benzo[c]phenanthridines via intramolecular cyclization of enamides

A new synthetic route towards planar 8,9-disubstituted benzo[c]phenanthridinium salts via Bischler-Napieralski cyclization of enamides is reported. Treatment of ketoester 1b with benzylamine/TiCl4 in dimethoxyethane, followed by acetylation with acetyl chloride afforded a mixture of naphthylamide 2 and E-enamide 3. Both enamides were efficiently cyclized by POCl3 in acetonitrile under reflux. While the planar benzo[c]phenanthridinium salt 4 was directly produced from 2, the E-enamide 3 gave the 3-arylisoquinolinium salt 5, which was reduced and intramolecular cyclized to yield the tetracyclic nucleus of these alkaloids.