156170-88-6Relevant articles and documents
Synthetic approach to 1,3-polymethyl function based on diastereoselective conjugate addition
Ogawa,Suemune,Sakai
, p. 1652 - 1654 (2007/10/02)
A new method for diastereo- and enantioselective preparation of 1,3- polymethyl functions was studied. The reaction of (1'R,2'R,5R)-(2E)-2'- hydroxycyclohexyl 5,9-dimethyl-2,8-decadienoate (6) with Me2 CuLi afforded a diastereomeric mixture of conjugate addition products ((3R,5R)-9 and (3S,5R)- 9) in a ratio of 77 to 23.