156173-93-2

Upstream product

• 15260-10-3 N-Boc-O-benzyl-L-threonine 
• 156173-89-6 (R)-4-<(S)-1-(benzyloxy)ethyl>-3-t-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidine 
• 156173-91-0 (R)-3-t-butoxycarbonyl-2,2-dimethyl-4-<(S)-1-(methylsulfonyl)ethyl>-1,3-oxazolidine 
• 156173-92-1 (R)-4-<(R)-1-azidoethyl>-3-t-butoxycarbonyl-2,2-dimethyl-1,3-oxazolidine 
• 156173-83-0 (4R)-4-[(R)-1-hydroxyethyl]-2,2-dimethyl-N-(tert-butoxycarbonyl)-1,3-oxazolidine 
• 156173-90-9 (R)-3-t-butoxycarbonyl-2,2-dimethyl-4-<(S)-1-hydroxyethyl>-1,3-oxazolidine 
• 79069-63-9 tert-butyl [(2R,3R)-3-(benzyloxy)-1-hydroxybutan-2-yl]carbamate 
• 2592-18-9 Boc-Thr-OH 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 156173-94-3 (2R,3R)-3-(benzyloxycarbonyl)amino-2-(t-butoxycarbonyl)amino-1-butanol 

Relevant academic research and scientific papers

Dehydrooligopeptides. XVII. Practical syntheses of all of the diastereomers of N,N-protected 2,3-diaminobutanoic acids from L- and D-threonine derivatives

Syntheses of all of the dioctereomers of 2,3-diaminobutanoic acids, found in some pedtide antibiotics and toxins, were accomplished. The four isomers were derived mainly through two pathways including S(N)2 inversions of the β-substituent of L- or D-threonine derivatives. The various protecting groups and effective nucleophiles for the S(N)2 inversion were examined.