156207-33-9Relevant academic research and scientific papers
Exploring the active site of phenylethanolamine N-methyltransferase: 3-alkyl-7-substituted-1,2,3,4-tetrahydroisoquinoline inhibitors
Grunewald, Gary L.,Romero, F. Anthony,Chieu, Alex D.,Fincham, Kelcie J.,Bhat, Seema R.,Criscione, Kevin R.
, p. 1261 - 1273 (2007/10/03)
A series of 3-alkyl-7-substituted-1,2,3,4-tetrahydroisoquinolines was synthesized and these compounds were evaluated for their PNMT inhibitory potency and affinity for the α2-adrenoceptor. 7-Nitro-, 7-bromo-, 7-aminosulfonyl-, or 7-N-2,2,2-trif
Reaction of N-Acyl-α-methoxyamines with Organozic Reagents. A Convenient Method for the Synthesis of Homoallylamines and β-Amino Esters.
Kise, Naoki,Yamazaki, Hiroki,Mabuchi, Toshirou,Shono, Tatsuya
, p. 1561 - 1564 (2007/10/02)
The reaction of N-acyl-α-methoxyamines with allyl-, propargyl-, and benzylzinc bromides and Reformatsky reagents proceeds in THF at room temperature.Homoallyl- and homopropargylamines and β-amino esters are synthesized in good yields.
