1562381-71-8Relevant articles and documents
Zn(II)- or Ag(I)-catalyzed 1,4-metathesis reactions between 3-en-1-ynamides and nitrosoarenes
Gawade, Sagar Ashok,Huple, Deepak B.,Liu, Rai-Shung
, p. 2978 - 2981 (2014/03/21)
Catalyst-dependent metathesis reactions between 3-en-1-ynamides and nitrosoarenes are described. Particularly notable are the unprecedented 1,4-metathesis reactions catalyzed by Ag(I) or Zn(II) to give 2-propynimidamides and benzaldehyde derivatives. With 3-en-1-ynamides bearing a cycloalkenyl group, 1,4-oxoimination products were produced efficiently. We have developed metathesis/alkynation cascades for unsubstituted 2-propynimidamides and benzaldehyde species generated in situ, to manifest 1,4-hydroxyimination reactions of 3-en-1-ynes. Both 1,4-oxoiminations and 1,4-hydroxyiminations increase the molecular complexity of products.