156245-57-7

Usage

Physical Properties

Yellow to orange liquid The chemical is a yellow to orange liquid, which is a description of its physical appearance.

Pungent Odor

1H-Pyrrole-2-carboxaldehyde, 4-(1,1-dimethylethyl)(9CI) has a pungent odor, which is a description of its smell.

Industrial Uses

Pharmaceuticals, agrochemicals, and dyes This chemical is primarily used in the production of pharmaceuticals, agrochemicals, and dyes, which are various industrial applications.

Flavoring Agent

Food industry 1H-Pyrrole-2-carboxaldehyde, 4-(1,1-dimethylethyl)(9CI) is used as a flavoring agent in the food industry due to its strong aroma, which is a description of its use in the food industry.

Chemical Reactivity

Ability to react with other chemicals This chemical is known for its ability to react with a variety of other chemicals, making it a versatile compound in various industrial applications.

Safety Precautions

Harmful if ingested or inhaled, causes skin and eye irritation It is important to handle and use 1H-Pyrrole-2-carboxaldehyde, 4-(1,1-dimethylethyl)(9CI) with caution, as it can be harmful if ingested or inhaled, and can cause irritation to the skin and eyes upon contact.

Upstream product

• 79-37-8 oxalyl dichloride 
• 7721-49-5 3-(tert-butyl)-1H-pyrrole 
• 109-97-7 pyrrole 
• 507-20-0 tertiary butyl chloride 
• 75866-92-1 N-((1H-pyrrol-2-yl)methylene)-N-methylmethanaminium hydrogen chloride 

Relevant academic research and scientific papers

Azines and imines of 4- and 5-t-Bu-pyrrole-2-aldehyde. A useful synthesis of the aldehydes

The preparation of 4- and 5-t-Bu-pyrrole-2-aldehyde can be brought about in a high yield and purity using Vilsmeier-Haack type reactions as conclusions to reaction sequences involving a 1-benzenesulfonyl directing group on pyrrole (4-substitution) or the formamidinium salt of pyrrole (5- substitution). Azines/imines were prepared and characterised.

Synthesis, structures and reactivity of 2-phosphorylmethyl-1H-pyrrolato complexes of titanium, yttrium and zinc

The reaction of secondary phosphines HPR2 (R = Ph, Cy) with pyrrole-2-aldehydes gives a new family of 2-phosphorylmethyl-1H-pyrroles as potentially chelating mono-anionic ligands. The reaction with Ti(NMe 2)4 affords octahedral Ti(NMe2) 2{NC4H2(4-R′)CH2P(O)R 2}2 (R′ = H, But). While the diphenylphosphoryl complexes adopt a configuration with trans-pyrrolato ligands, the dicyclohexyl analogue prefers an all-cis conformation, with profound consequences on metal-ligand bonding. The reaction of sterically undemanding HNC4H3CH2P(O)Ph2 with Y[N(SiHMe 2)2]3(THF)2 give the homoleptic complex Y[NC4H3CH2P(O)Ph2] 3; mixed-ligand intermediates Y[N(SiHMe2) 2]2(N-O) and Y[N(SiHMe2)2](N-O) 2 were identifiable but could not be isolated. The bulky ligand HNC4H2(5-But)CH2P(O)Ph2 does not react with Ti(NMe2)4 but protolyses Zn[N(SiMe3)2]2 to give a 1: 2 complex Zn(N-O)2 as the only isolable product. On the other hand, its reaction with Y[N(SiHMe2)2]3(THF)2 affords the mono-amido complex Y{N(SiHMe2)2}{NC 4H3(5-But)CH2P(O)Ph 2}2 which shows good activity for the ring-opening polymerisation of cyclic esters. The Royal Society of Chemistry 2009.

Synthesis of 4-substituted pyrrole-2-carbaldehyde compounds

The invention relates to an a process for making a 4-substituted pyrrole-2-carbaldehyde compound comprising reacting: a. a pyrrole-2-carbaldehyde compound; and b. an alkylating agent; c. in the presence of at least one catalyst; to form a 4-alkyl substituted pyrrole-2-carbaldehyde compound.