1562498-41-2Relevant academic research and scientific papers
Discovery of 6-aryl-azabenzimidaoles that inhibit the TBK1/IKK-ε kinases
Johannes, Jeffrey W.,Chuaqui, Claudio,Cowen, Scott,Devereaux, Erik,Gingipalli, Lakshmaiah,Molina, Audrey,Wang, Tao,Whitston, David,Wu, Xiaoyun,Zhang, Hai-Jun,Zinda, Michael
, p. 1138 - 1143 (2014/03/21)
The discovery and optimization of a series of 6-aryl-azabenzimidazole inhibitors of TBK1 and IKK-ε is described. Various internal azabenzimidazole leads and reported TBK1/IKK-ε inhibitors were docked into a TBK1 homology model. The resulting overlays insp
