15626-16-1Relevant academic research and scientific papers
Fluorescent-labeled analogues of cholesterol
Grechishnikova,Molotkovsky
, p. 394 - 399 (2007/10/03)
Starting from pregnenolone acetate, new fluorescent analogues of cholesterol, (22E, 20R)-3β-hydroxy-23-(9-anthryl)-24-norchola-5,22-diene and its 205-isomer, were synthesized. They bear an anthrylvinyl group instead of the C22-C27 fragment of the sterol alkyl chain and possess fluorescent properties characteristic of anthrylvinyl probes. Both analogues can be easily incorporated into the phospholipid bilayer and used for the study of membrane systems.
Partial Synthesis of "Sargasterol" and (20S)-Cholesterol
Sucrow, Wolfgang,Nooy, Michael van
, p. 1897 - 1906 (2007/10/02)
The data of the synthetic (20S)-3β-hydroxy-5-cholestan-24-one (5b) and its acetate 5a differ significantly from those given for the degradation product of "sargasterol".The compounds 5a,b were converted into the E/Z-isomeric (20S)-stigmasta-5,24(28)-dien-3β-ols 8b, 9b, into their acetates 8a, 9a, and into (20S)-cholesterol (10b). (20S)-cholesterol acetate (10a) shows a lower melting point than that which is given in literature.
Preparation of 3β-hydroxy-27-norcholest-5-ene-25-one and intermediates thereof
-
, (2008/06/13)
A process for preparing 3β-hydroxy-27-norcholest-5-ene-25-one, a useful intermediate in the synthesis of 25-acetoxy vitamin D3, novel intermediates, and preparation thereof are disclosed.
Titration of sterol double bonds with dibromopyridine sulfate
Rosenstein,Caruso,Kircher
, p. 297 - 300 (2007/10/09)
Cis and trans 22 dehydrocholesteryl acetates and cis and trans 22 cholesten 3β yl acetates were prepared and compared to Δ22 phytosterylacetates by titration with dibromopyridine sulfate. The cholesterol derivatives absorbed close to the theore
