156295-31-7

Basic information

• Product Name: (S)-8-Acetoxymethyl-4-benzyloxy-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester
• Synonyms: (S)-8-Acetoxymethyl-4-benzyloxy-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester
• CAS NO: 156295-31-7
• Molecular Weight: 508.571
• Mol File: 156295-31-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-8-Acetoxymethyl-4-benzyloxy-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-8-Acetoxymethyl-4-benzyloxy-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester(156295-31-7)
• EPA Substance Registry System: (S)-8-Acetoxymethyl-4-benzyloxy-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester(156295-31-7)

Safety Data

• Hazardous Substances Data: 156295-31-7(Hazardous Substances Data)

Upstream product

• 156295-30-6 (S)-3-Acetoxymethyl-6-benzyloxy-5-((E)-2-methoxycarbonyl-1-methyl-vinylamino)-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester 
• 105-45-3 acetoacetic acid methyl ester 

Downstream Products

• 156295-32-8 (S)-4-Benzyloxy-8-hydroxymethyl-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester 
• 153925-97-4 3-methoxycarbonyl-2-methylduocarmycin A 
• 154889-68-6 3-methoxycarbonyl-2-methyl-8-O-(4-methyl-1-piperazinylcarbonyl)duocarmycin B2 
• 156295-33-9 (S)-4-Benzyloxy-8-chloromethyl-2-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-1,6-dicarboxylic acid 6-tert-butyl ester 1-methyl ester 
• 205652-13-7 (S)-8-Chloromethyl-4-hydroxy-2-methyl-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-3,6,7,8-tetrahydro-pyrrolo[3,2-e]indole-1-carboxylic acid methyl ester 

Relevant articles and documents

Novel syntheses of optically active CC-1065, U-73,975(adozelesin), U-80,244(carzelesin), U-77,779(bizelesin), KW-2189, and DU-86

The title syntheses were achieved by the method featuring oxidative cyclization of the enamino esters [(S)-13 and (S)-24] derived from the 5-aminoindoline [(5)-12], acylation with various structural types of indole-2-carboxylic acids, and formation of cyclopropapyrroloindole moieties.