156301-31-4Relevant academic research and scientific papers
A Practical Alternative to Sulfonyl Activation of Aziridines: Ring-Opening of N-Diphenylphosphinoyl Aziridines by Carbon Nucleophiles
Osborn, Helen M. I.,Sweeney, J. B.,Howson, William
, p. 2739 - 2742 (1994)
The ring-opening reaction of N-diphenylphosphinoylaziridines by Copper (I)-modified Grignard reagents proceeds in good to excellent yield and with complete regiospecificity.
Preparation and ring-opening reactions of N-diphenylphosphinyl aziridines
Cantrill, Alex A.,Osborn, Helen M. I.,Sweeney, Joseph
, p. 2181 - 2208 (2007/10/03)
Monochiral N-Diphenyphosphinyl aziridines ('N-Dpp azinidines') may efficiently be prepared from monochiral 2-aminoalcohols. Such aziridines undergo ring-opening reaction with a variety of nucleophiles in good yield. Dephosphinylation is accomplished under mild conditions.
