A Practical Alternative to Sulfonyl Activation of Aziridines: Ring-Opening of N-Diphenylphosphinoyl Aziridines by Carbon Nucleophiles

DOI: 10.1016/S0040-4039(00)77020-1

Source and publish data:

Tetrahedron Letters p. 2739 - 2742 (1994)

Update date:2022-08-03

Topics:

Authors:

Osborn, Helen M. I.

Sweeney, J. B.

Howson, William

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)77020-1

The ring-opening reaction of N-diphenylphosphinoylaziridines by Copper (I)-modified Grignard reagents proceeds in good to excellent yield and with complete regiospecificity.

Full text of DOI:10.1016/S0040-4039(00)77020-1

Products guided by the article

Product name:(S)-1-cyclopentyl-2-(diphenylphosphinamido)-4-methylpentane

Cas No:156301-31-4

R&D Labs maybe for 156301-31-4

Nanjing Chemipioneer Pharma&Tech Co.,Ltd

website:http://www.chemipioneer.com.cn

Contact:+86-25-52685700

Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
GBXF SILICONES CO.,LTD

website:http://www.gbxfsilicones.com/

Contact:86-25-68900673

Address:He Country Provincial Fine Chemical Industrial Park of Chaohu city,Anhui province,China
Changsha Easchem Co.,Limited

website:http://www.easchem.com

Contact:+86-731-89722861 89722891

Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
Shanghai Coupling Pharmaceutical R&D Co., Ltd.(expird)

Contact:+86 021 50106671

Address:403 Room No.4 Buiding, No. 526 Ruiqing Road, Shanghai Zhangjiang Hi-Tech Park
HANWAYS CHEMPHARM CO.,LIMITED

website:http://www.hanwayschem.com

Contact:+86-18502787239(whatsapp)-

Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China

Relevant to this article

Platform for Ring-Fluorinated Benzoheterole Derivatives: Palladium-Catalyzed Regioselective 1,1-Difluoroallylation and Heck Cyclization

Doi:10.1021/acs.orglett.5b03390
(2016)
Catalytic epoxidation of hindered olefins with dioxygen. Fast oxygen atom transfer to olefin cation radicals from nitrogen oxides

Doi:10.1021/ja953786n
(1996)
A novel entry toward 2-imino-1,3-thiazolidines and 2-imino-1,3-thiazolines by ring transformation of 2-(thiocyanomethyl)aziridines

Doi:10.1021/jo048486f
(2005)
Transition-Metal-Free Catalytic Hydrodefluorination of Polyfluoroarenes by Concerted Nucleophilic Aromatic Substitution with a Hydrosilicate

Doi:10.1002/anie.201708003
(2017)
Regioselectivity in the 1,3-Dipolar Cycloaddition of Nitrile Oxides to N-(3,5-Dichlorophenyl)itaconimide

Doi:10.1007/BF00811316
(1994)
Synthesis and biological activities of the optical isomers of (±)-4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]me thyl]benzamide (Mosapride)

Doi:10.1248/cpb.42.877
(1994)

Article Doi