1563184-79-1

Basic information

• Product Name: ((5-(4-methylpiperazine-1-carbonyl)-2-(methylsulfonyl)-4-nitrophenyl)azanediyl)bis(ethane-2,1-diyl)dimethanesulfonate
• Synonyms: ((5-(4-methylpiperazine-1-carbonyl)-2-(methylsulfonyl)-4-nitrophenyl)azanediyl)bis(ethane-2,1-diyl)dimethanesulfonate
• CAS NO: 1563184-79-1
• Molecular Weight: 586.665
• Mol File: 1563184-79-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((5-(4-methylpiperazine-1-carbonyl)-2-(methylsulfonyl)-4-nitrophenyl)azanediyl)bis(ethane-2,1-diyl)dimethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: ((5-(4-methylpiperazine-1-carbonyl)-2-(methylsulfonyl)-4-nitrophenyl)azanediyl)bis(ethane-2,1-diyl)dimethanesulfonate(1563184-79-1)
• EPA Substance Registry System: ((5-(4-methylpiperazine-1-carbonyl)-2-(methylsulfonyl)-4-nitrophenyl)azanediyl)bis(ethane-2,1-diyl)dimethanesulfonate(1563184-79-1)

Safety Data

• Hazardous Substances Data: 1563184-79-1(Hazardous Substances Data)

Upstream product

• 254878-95-0 3-fluoro-4-(methylsulfonyl)benzaldehyde 
• 34036-07-2 3,4 difluorobenzaldehyde 
• 109-01-3 1-methyl-piperazine 
• 1563184-60-0 5-(bis(2-((methylsulfonyl)oxy)ethyl)amino)-4-(methylsulfonyl)-2-nitrobenzoic acid 
• 1563184-59-7 tert-butyl 5-(bis(2-((methylsulfonyl)oxy)ethyl)amino)-4-(methylsulfonyl)-2-nitrobenzoate 
• 1563184-57-5 tert-butyl 5-(bis(2-hydroxyethyl)amino)-4-(methylsulfonyl)-2-nitrobenzoate 
• 1563184-56-4 tert-butyl 5-fluoro-4-(methylsulfonyl)-2-nitrobenzoate 
• 185945-88-4 3-fluoro-4-(methylsulfonyl)benzoic acid 

Downstream Products

• 1563184-78-0 (5-(bis(2-bromoethyl)amino)-4-(methylsulfonyl)-2-nitrophenyl)(4-methylpiperazine-1-yl)methanone 

Relevant articles and documents

NOVEL PRODRUGS AND METHODS OF USE THEREOF

The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are substantially resistant to human AKR1C3 enzyme metabolism, methods of cell ablation using said com