156335-37-4

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 4-oxo-1,4-dihydropy is used as a key intermediate in the synthesis of various drugs and experimental research. Its unique structure and reactivity allow for the development of new compounds with therapeutic applications.
Used in Organic Synthesis:
Ethyl 4-oxo-1,4-dihydropy serves as a versatile building block in the field of organic synthesis. It is particularly useful in the preparation of various fine chemicals and biologically active compounds, contributing to the advancement of chemical research and the discovery of novel substances with potential applications.
Used in Development of New Compounds:
Due to its functional groups and reactivity, Ethyl 4-oxo-1,4-dihydropy is of great interest to chemists and researchers for the development of new compounds with potential pharmacological properties. Its unique structure allows for the exploration of various chemical reactions and the synthesis of innovative molecules with therapeutic potential.

InChI:InChI=1/C10H10N2O3/c1-2-15-10(14)7-6-11-12-5-3-4-8(12)9(7)13/h3-6,11H,2H2,1H3

Upstream product

• 765-39-9 1H-pyrrol-1-amine 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 156335-36-3 diethyl (1-pyrrolyl)aminomethylenepropanedioate 

Downstream Products

• 888720-26-1 pyrrolo[1,2-b]pyridazin-4(1H)-one 
• 1187875-95-1 4-(4-nitrophenoxy)-pyrrolo[1,2-b]pyridazine 
• 1187875-97-3 4-(pyrrolo[1,2-b]pyridazin-4-yloxy)benzenamine 
• 1221713-71-8 N-(3-fluoro-4-(5-phenylpyrrolo[1,2-b]pyridazin-4-yloxy)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide 
• 1221714-55-1 1-(4-(2-fluoro-4-nitrophenoxy)pyrrolo[1,2-b]pyridazin-5-yl)ethanone 
• 1221714-45-9 4-(5-bromopyrrolo[1,2-b]pyridazin-4-yloxy)-3-fluoroaniline 
• 1221714-44-8 5-bromo-4-(2-fluoro-4-nitrophenoxy)pyrrolo[1,2-b]pyridazine 
• 888720-27-2 4-(2-fluoro-4-nitrophenoxy)pyrrolo[1,2-b]pyridazine 
• 1221713-69-4 N-(4-(5-bromopyrrolo[1,2-b]pyridazin-4-yloxy)-3-fluorophenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide 
• 156335-40-9 4-ethoxypyrrolo<1,2-b>pyridazine-3-carboxylic acid 
• 156335-30-7 1,4-dihydro-4-oxopyrrolo<1,2-b>pyridazine-3-carboxylic acid 

Relevant academic research and scientific papers

CONDENSED HETEROCYCLIC COMPOUND

Provided is a compound represented by the following formula, or a salt thereof: [wherein each symbol is as defined herein.].

HETEROCYCLIC COMPOUND AS PROTEIN KINASE INHIBITOR

Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met, pharmaceutical compositions containing the same, and methods for using the compound.

AURORA KINASE MODULATORS AND METHOD OF USE

The present invention relates to chemical compounds having a general formula (I) wherein A1-5 and 7-8, D', L1, L2, R1, R3, R6-8, n and o are defined herein, and synthetic intermediates, which are capable of modulating the activity of Aurora kinase proteins and, thereby, influencing various disease states and conditions related to the activities of Aurora kinases. For example, the compounds are capable of influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.

Synthesis of 1,4-dihydro-4-oxopyrrolo[1,2-b]pyridazine-3-carboxylic acids and 1,4-dihydro-4-oxoimidazo[1,5-b]pyridazine-3-carboxylic acids as potential antibacterial agents

To check the antibacterial potential of two families of aza analogues of the quinolones, 1,4-dihydro-4-oxopyrrolo[1,2-b]pyridazine-3-carboxylic acids and 1,4-dihydro-4-oxoimidazo[1,5-b]pyridazine-3-carboxylic acids, we have prepared a few derivatives in these families using N-aminopyrrole and N-aminoimidazole derivatives as starting building blocks and the classical pathways of the quinolone series. The compounds showed no interesting antibacterial activity.