156370-61-5

Basic information

• Product Name: 3-(isopropylamino)-1-phenyl-1-propanol
• CAS NO: 156370-61-5
• Molecular Weight: 193.289
• Mol File: 156370-61-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(isopropylamino)-1-phenyl-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(isopropylamino)-1-phenyl-1-propanol(156370-61-5)
• EPA Substance Registry System: 3-(isopropylamino)-1-phenyl-1-propanol(156370-61-5)

Safety Data

• Hazardous Substances Data: 156370-61-5(Hazardous Substances Data)

Upstream product

• 936-59-4 3-chloropropiophenone 
• 100-52-7 benzaldehyde 
• 67747-26-6 N-Isopropyl-2-phenylsulfanylethylamine 
• 18776-12-0 3-chloro-1-phenyl-propan-1-ol 
• 75-31-0 isopropylamine 

Downstream Products

• 156370-50-2 N-isopropyl-2-phenylazetidine 
• 87462-11-1 N-isopropyl-3-phenylpropan-1-amine 

Relevant articles and documents

Functionalized organolithium compounds of DTBB-catalyzed sulfur-lithium exchange

The successive reaction of β- or γ-hydroxy or amino phenyl thioethers (1,4) with butyllithium and an excess of lithium powder in the presence of a catalytic amount of DTBB in THF at - 78°C leads to the formation of the corresponding β- or γ-functionalized organolithium compounds 2 or 5, respectively, which by treatment with different electrophiles [D2O, t- BuCHO, PhCHO, Me2CO, (CH2)4CO, (CH2)5CO] at temperatures ranging between - 78°C and room temperature yields, after hydrolysis with water, the expected functionalized alcohols or amines 3 or 6, respectively, in a completely regioselective manner.