156424-89-4

Upstream product

• 156424-88-3 6,7-bis-(3,4-dimethoxyphenyl)-indolizine-5,8-dione 
• 2859-78-1 4-Bromoveratrole 
• 156424-87-2 2,3-bis-(3,4-dimethoxyphenyl)-4-(1-pyrrolo)-4-trimethylsiloxycyclobutenone 
• 157143-35-6 3,4-bis-dimethoxyphenylcyclobutenedione 

Downstream Products

• 156424-90-7 6,7-bis-(3,4-dimethoxyphenyl)-1,2,3-trihydro-8-trifluoromethylsulfonyl-indolizine-5-one 
• 26503-67-3 (+/-)-6,7-di(3,4-dimethoxyphenyl)-1,2,3,5,8,8a-hexahydro-indolizine 
• 156424-91-8 6,7-bis-(3,4-dimethoxyphenyl)-1,2,3-trihydroindolizine-5-one 

Relevant academic research and scientific papers

Efficient synthesis of a new structural phenanthro[9,10,3′,4′] indolizidine starting from pyrrole

(Chemical Equation Presented) A new structural phenanthroindolizidine, 2,3,6,7-tetramethoxyphenanthro[9,10,3′,4′]indolizidine, has been synthesized efficiently from pyrrole. An important feature of this synthesis is that intramolecular oxidative coupling

Synthesis of (±)-septicine

The total synthesis of the indolizidine alkaloid, (±)-septicine (5) (27% overall yield) in 8 steps from dimethyl squarate is presented. The key step of the synthesis involves the ring expansion of 2,3-bis-(3,4-dimethoxyphenyl)-4-(1-pyrrolo)cyclobutenone 12 to the corresponding indolizine-5,8-dione 6. The synthesis is highly convergent and thus could be used for the synthesis of a variety of analogs.