156567-57-6

Basic information

• Product Name: N-PROPYLZINC BROMIDE
• Synonyms: N-PROPYLZINC BROMIDE;PROPYLZINC BROMIDE;PROPYLZINC BROMIDE, 0.5M SOLUTION IN TET RAHYDROFURAN;propylzinc bromide solution;Propylzinc bromide solution 0.5 in THF;n-Propylzinc broMide, 0.5M in THF, packaged under Argon in resealable CheMSeal^t bottles;Propylzinc broMide solution 0.5 M in THF;Propylzinc bromide, 0.50 M in THF
• CAS NO: 156567-57-6
• Molecular Formula: C₃H₇BrZn
• Molecular Weight: 188.38
• Product Categories: Alkyl;Organozinc Halides;Reike and Organozinc Reagents;Chemical Synthesis;Organometallic Reagents;Organozinc Halides;Rieke and Organozinc Reagents
• Mol File: 156567-57-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: 1 °F
• Appearance: /
• Density: 0.947 g/mL at 25 °C
• Storage Temp.: 2-8°C
• Sensitive: Air Sensitive
• CAS DataBase Reference: N-PROPYLZINC BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PROPYLZINC BROMIDE(156567-57-6)
• EPA Substance Registry System: N-PROPYLZINC BROMIDE(156567-57-6)

Safety Data

• Hazard Codes: F,Xn
• Statements: 14-19-22-36/37/38-40-36/37-11
• Safety Statements: 16-26-33-36/37/39-43-45-36/37
• RIDADR: UN 3399 4.3/PG 2
• HazardClass: 4.3
• Hazardous Substances Data: 156567-57-6(Hazardous Substances Data)

Usage

General Description

N-PROPYLZINC BROMIDE is a chemical compound that consists of a zinc atom bonded to a propyl group and a bromide ion. It is commonly used as a reagent in organic synthesis reactions, particularly in the formation of carbon-carbon bonds. N-PROPYLZINC BROMIDE is a highly reactive and flammable compound that should be handled with caution and stored in a well-ventilated area. It is also moisture sensitive, meaning it should be protected from exposure to water or humidity. This chemical is commonly used in the pharmaceutical and chemical industries for the production of various organic compounds and intermediates.

InChI:InChI=1/C3H7.BrH.Zn/c1-3-2;;/h1,3H2,2H3;1H;/q;;+1/p-1/rC3H7BrZn/c1-2-3-5-4/h2-3H2,1H3

Upstream product

• 927-77-5 n-propylmagnesium bromide 
• 106-94-5 propyl bromide 
• 7440-66-6 zinc 

Downstream Products

• 1206124-58-4 ethyl 2-(7-(4-propyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate 
• 614-14-2 1-Phenyl-1-butanol 
• 55824-11-8 CBGV 
• 83036-51-5 2-((E)-3,7-Dimethyl-octa-2,6-dienyl)-1,3-dimethoxy-5-propyl-benzene 
• 24274-48-4 cannabidivarin 

Relevant articles and documents

Direct transformation of aryl 2-pyridyl esters to secondary benzylic alcohols by nickel relay catalysis

A direct transformation of aryl esters to secondary benzylic alcohols via tandem Ni-catalyzed cross-coupling reactions of aromatic 2-pyridyl esters with alkyl zinc reagents and carbonyl group reduction by Ni-H species is achieved. Preliminary mechanistic studies reveal that the Ni-H species is generated in situ via β-hydride elimination of the Negishi reagents. The reaction is catalyzed by bench-stable nickel salts under mild conditions with wide functional group tolerance.

Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion

CMPF (2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid) is a metabolite that circulates at high concentrations in type 2 and gestational diabetes patients. Further, human clinical studies suggest it might have a causal role in these diseases. CMPF inhibits insulin secretion in mouse and human islets in vitro and in vivo in rodents. However, the metabolic fate of CMPF and the relationship of structure to effects on insulin secretion have not been significantly studied. The syntheses of CMPF and analogues are described. These include isotopically labeled molecules. Study of these materials in vivo has led to the first observation of a metabolite of CMPF. In addition, a wide range of CMPF analogues have been prepared and characterized in insulin secretion assays using both mouse and human islets. Several molecules that influence insulin secretion in vitro were identified. The molecules described should serve as interesting probes to further study the biology of CMPF.

Synthese et reactivite de quelques organozinciques dans des solvants peu courants en chimie organometallique

The use of solvents strange to organometallic chemistry viz. carbonic or phosphoric esters, or sulfolane allows zinc to react with organic halides, which are usually unreactive towards this metal.The ractions of the organozinc compounds thus synthesised (