156569-08-3

Upstream product

• 100-51-6 benzyl alcohol 
• 150934-78-4 Diethyl 4-(benzyloxy)-3-hydroxybutanephosphonate 
• 683-08-9 Diethyl methylphosphonate 
• 2930-05-4 Benzyloxymethyl-oxiran 
• 131853-16-2 2-amino-6-chloropurine sodium salt 
• 150943-45-6 (4-Benzyloxy-3-chloromethoxy-butyl)-phosphonic acid diethyl ester 

Downstream Products

• 156569-09-4 9-<(1-benzyloxy-3-diethylphosphono)-1-propyloxymethyl>guanine 
• 156569-11-8 2-amino-6-hydroxyethylthio-9-<(1-benzyloxymethyl-3-diethylphosphono)-1-propyloxymethyl>-9H-purine 
• 156569-12-9 2-amino-6-hydroxyethylthio-9-<(1-benzyloxymethyl-3-phosphono)-1-propyloxymethyl>-9H-purine 

Relevant academic research and scientific papers

Synthesis of acyclonucleoside phosphonates as antiviral agents against cytomegalovirus

Phosphonic acid analogs of ACV and DHPG that are isosteric with ACV phosphate and DHPG phosphate have been synthesized and evaluated for antiviral activity against human, murine, and guinea pig strains of cytomegalovirus. The phosphonates showed high activity against all of the strains. They were also evaluated against a DHPG resistant strain of human cytomegalovirus. Although the activity dropped considerably, significant antiviral activity was still evident.