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CAS

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1566-15-0

PHOSPHORAMIDEMUSTARD, also known as N,N-Bis(2-chloroethyl)phosphorodiamidic Acid Cyclohexylamine Salt, is a cytotoxic metabolite derived from Cyclophosphamide (C988580). It is a chemical compound with significant biological activity, primarily recognized for its role in the pharmaceutical industry due to its cytotoxic properties.

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  • N,N-bis(2-chloroethyl)phosphorodiamidic acid compound with cyclohexanamine (1:1)

    Cas No: 1566-15-0

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  • 1566-15-0 Structure

  • Basic information

    1. Product Name: PHOSPHORAMIDEMUSTARD
    2. Synonyms: Ai3-51834;Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-, compd. with cyclohexanamine(1:1) (9ci);Phosphorodiamidic acid, N,N-bis(2-chloroethyl)-, compound with cyclohexanamine (1:1);N,N-Bis(2-chloroethyl)phosphorodiaMidic Acid CyclohexylaMine Salt
    3. CAS NO:1566-15-0
    4. Molecular Formula: C4H11Cl2N2O2P*C6H13N
    5. Molecular Weight: 320.196221
    6. EINECS: N/A
    7. Product Categories: Amino Acids & Derivatives, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 1566-15-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 363.5°Cat760mmHg
    3. Flash Point: 173.6°C
    4. Appearance: /
    5. Density: g/cm3
    6. Vapor Pressure: 2.84E-06mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
    9. Solubility: Chloroform (Slightly), Methanol (Slightly)
    10. Stability: Moisture Sensitive
    11. CAS DataBase Reference: PHOSPHORAMIDEMUSTARD(CAS DataBase Reference)
    12. NIST Chemistry Reference: PHOSPHORAMIDEMUSTARD(1566-15-0)
    13. EPA Substance Registry System: PHOSPHORAMIDEMUSTARD(1566-15-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1566-15-0(Hazardous Substances Data)

1566-15-0 Usage

Uses

Used in Pharmaceutical Industry:
PHOSPHORAMIDEMUSTARD is used as a cytotoxic agent for its ability to inhibit cell growth and proliferation, making it a crucial component in the development of cancer treatments. Its cytotoxic nature allows it to target and destroy cancer cells, thus playing a vital role in the treatment of various types of cancer.
Used in Cancer Treatment:
PHOSPHORAMIDEMUSTARD is utilized as a chemotherapeutic agent for its effectiveness in treating a wide range of cancers. It is particularly useful in the treatment of solid tumors, such as those found in the breast, lung, and ovaries, as well as leukemia and lymphoma. The compound works by disrupting the DNA of cancer cells, preventing them from dividing and spreading.
Used in Research and Development:
In addition to its direct application in cancer treatment, PHOSPHORAMIDEMUSTARD is also used as a research tool in the development of new cancer therapies. Its cytotoxic properties make it a valuable compound for studying the mechanisms of cell death and the development of resistance to chemotherapy in cancer cells. This research can lead to the discovery of new drugs and treatment strategies to combat cancer more effectively.

Check Digit Verification of cas no

The CAS Registry Mumber 1566-15-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,5,6 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1566-15:
(6*1)+(5*5)+(4*6)+(3*6)+(2*1)+(1*5)=80
80 % 10 = 0
So 1566-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H13N.C4H11Cl2N2O2P/c7-6-4-2-1-3-5-6;5-1-3-8(4-2-6)11(7,9)10/h6H,1-5,7H2;1-4H2,(H3,7,9,10)

1566-15-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name amino-[bis(2-chloroethyl)amino]phosphinic acid,cyclohexanamine

1.2 Other means of identification

Product number -
Other names n,n-bis(2-chloroethyl)phosphorodiamidic acid-cyclohexanamine(1:1)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1566-15-0 SDS

1566-15-0Upstream product

1566-15-0Relevant articles and documents

Novel antitumor aldophosphamide analogs

-

, (2008/06/13)

A compound having the structure: STR1 wherein R is CH3, C2 H5, C3 H7, t--C4 H9 or C6 H5 ; R1 is NH2, NHCH3, NHC2

Selective elimination of malignant cells from bone marrow by bis (acyloxy) propylphosphoramidates

-

, (2008/06/13)

A method for purging tumor cells from bone marrow of a host, the method comprising extracting bone marrow cells from the host; treating extracted bone marrow cells with a therapeutic level of a compound having the structure: STR1 wherein R is CH3/su

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