156602-61-8Relevant academic research and scientific papers
Benzylic C(sp3)-H Functionalization for C-N and C-O Bond Formation via Visible Light Photoredox Catalysis
Pandey, Ganesh,Laha, Ramkrishna,Singh, Deepak
, p. 7161 - 7171 (2016)
A visible light mediated highly selective benzylic C-H bond functionalization for intermolecular C-N and C-O bond formation is reported. This cross-dehydrogenative coupling reaction demonstrates a straightforward protocol for incorporating the heteroaromatics to the benzylic position. Benzylic oxidation of various alkyl aryls to corresponding carbonyl compounds has also been reported.
Benzotriazole-mediated synthesis of α-di- and α-trisubstituted ethers and sulfides
Katritzky,Jurczyk,Szajda,Shcherbakova,Lam
, p. 499 - 504 (2007/10/02)
Ethylaryl- and diethylaryl(benzotriazol-1-yl)methanes, obtained by mono- or dialkylation of substituted (benzotriazol-1-ylmethyl)benzenes, react with sodium alkoxides, phenol and thiophenol to yield the corresponding α-di- and α-trisubstituted ethers and
The Chemistry of Some 1-(α-Fluoroalkyl)Benzotriazoles
Katritzky, A.R.,Szajda, M.,Lam, J.N.
, p. 1243 - 1250 (2007/10/02)
1-(α-Fluoroalkyl)benzotriazoles are formed in high yields by treatment of their chloro precursors with potassium fluoride in 18-crown-6.The fluorine atom can then be displaced by methoxyarenes in the presence of a Lewis acid to afford 4-(α-substitutedalkyl)methoxyarenes. Key words: fluorination, methoxyarenes, aromatic substitution, benzyl ethers
