Welcome to LookChem.com Sign In|Join Free

CAS

  • or

156635-05-1

BIBB 515 is a selective inhibitor of the protein kinase p38α, which is crucial in regulating cellular responses to stress, inflammation, and apoptosis. It has been extensively studied for its potential therapeutic applications in various diseases, including inflammatory and autoimmune disorders, as well as cancer. BIBB 515 has demonstrated promising anti-inflammatory and anti-tumor effects in preclinical studies, positioning it as a potential candidate for the development of new drugs targeting p38α. Its selectivity for p38α over other kinases also makes it a valuable tool for studying the specific functions of p38α in cellular processes.

156635-05-1 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • 1-(4-chlorobenzoyl)-4-{[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]methylidene}piperidine

    Cas No: 156635-05-1

  • USD $ 1.9-2.9 / Gram

  • 100 Gram

  • 1000 Metric Ton/Month

  • Chemlyte Solutions
  • Contact Supplier
  • 156635-05-1 Structure

  • Basic information

    1. Product Name: BIBB 515
    2. Synonyms: BIBB 515;(4-chlorophenyl)-[4-[[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]methylidene]piperidin-1-yl]methanone
    3. CAS NO:156635-05-1
    4. Molecular Formula: C22H21ClN2O2
    5. Molecular Weight: 380.86734
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 156635-05-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 586.5±50.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.26±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 4.72±0.50(Predicted)
    10. CAS DataBase Reference: BIBB 515(CAS DataBase Reference)
    11. NIST Chemistry Reference: BIBB 515(156635-05-1)
    12. EPA Substance Registry System: BIBB 515(156635-05-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 156635-05-1(Hazardous Substances Data)

156635-05-1 Usage

Uses

Used in Pharmaceutical Industry:
BIBB 515 is used as a therapeutic agent for the treatment of inflammatory and autoimmune disorders due to its potent anti-inflammatory effects. Its ability to selectively inhibit p38α makes it a promising candidate for the development of new drugs targeting this protein kinase.
Used in Oncology:
BIBB 515 is used as an anti-tumor agent for the treatment of various types of cancer. Its anti-tumor effects have been demonstrated in preclinical studies, making it a potential candidate for the development of new cancer therapies.
Used in Research:
BIBB 515 is used as a research tool for studying the specific functions of p38α in cellular processes. Its selectivity for p38α over other kinases allows researchers to gain a deeper understanding of the role of this protein kinase in various biological pathways and disease mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 156635-05-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,6,3 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 156635-05:
(8*1)+(7*5)+(6*6)+(5*6)+(4*3)+(3*5)+(2*0)+(1*5)=141
141 % 10 = 1
So 156635-05-1 is a valid CAS Registry Number.

156635-05-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-chlorophenyl)-[4-[[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]methylidene]piperidin-1-yl]methanone

1.2 Other means of identification

Product number -
Other names (4-Chloro-phenyl)-{4-[4-(4,5-dihydro-oxazol-2-yl)-benzylidene]-piperidin-1-yl}-methanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:156635-05-1 SDS

156635-05-1Downstream Products

156635-05-1Relevant articles and documents

Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation

-

, (2008/06/13)

The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula STR1 (wherein n, m, p, A, W1, W2, X, Y, and R1 to R11 are as defined in claim 1) and the isomers, isomer mixtures and salts thereof, which have useful properties, in particular an inhibitory effect on cholesterol biosynthesis.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 156635-05-1