144947-47-7

Basic information

• Product Name: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE
• Synonyms: 1-(4-CHLOROBENZOYL)-4-PIPERIDONE;1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE;1-(4-Chlorobenzoyl)-4-Piperidinone
• CAS NO: 144947-47-7
• Molecular Formula: C₁₂H₁₂ClNO₂
• Molecular Weight: 237.68
• Mol File: 144947-47-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 417.7°Cat760mmHg
• Flash Point: 206.4°C
• Appearance: /
• Density: 1.298g/cm³
• Vapor Pressure: 3.48E-07mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE(144947-47-7)
• EPA Substance Registry System: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE(144947-47-7)

Safety Data

• Hazardous Substances Data: 144947-47-7(Hazardous Substances Data)

Usage

General Description

1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE is a chemical compound with the molecular formula C13H14ClNO2. It is a piperidinone derivative with a 4-chlorobenzoyl group attached to the piperidine ring. 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE has potential pharmacological activities and is often used as an intermediate in the synthesis of various pharmaceuticals. Its structure and properties make it a valuable building block for the production of a wide range of drugs, including antipsychotics, antidepressants, and analgesics. In addition, research has shown that 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE may also have anti-inflammatory and analgesic effects, making it a promising candidate for further drug development.

InChI:InChI=1/C12H12ClNO2/c13-10-3-1-9(2-4-10)12(16)14-7-5-11(15)6-8-14/h1-4H,5-8H2

Upstream product

• 40064-34-4 4-piperidone monohydrochloride monohydrate 
• 122-01-0 4-chloro-benzoyl chloride 
• 41979-39-9 4-piperidone hydrochloride 

Downstream Products

• 355006-67-6 C₁₂H₁₁ClFNO₂ 
• 355006-70-1 1-(4-chlorobenzoyl)-4,4-dimethoxy-3-fluoropiperidine 
• 1036037-75-8 C₂₆H₃₁ClN₆O₂ 
• 156635-05-1 BIB₅₁₅ 

Relevant articles and documents

Subsitituted 1,4,8- triazaspiro [4,5]decan-2-one compounds

Novel 1,4,8-triazaspiro[4,5]decan-2-one compounds corresponding to formula I processes for the preparation thereof, related methods of treatment and pharmaceutical formulations containing such compounds.

Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation

The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula STR1 (wherein n, m, p, A, W1, W2, X, Y, and R1 to R11 are as defined in claim 1) and the isomers, isomer mixtures and salts thereof, which have useful properties, in particular an inhibitory effect on cholesterol biosynthesis.