156640-14-1

Basic information

• Product Name: N-[(1-benzyl-5-oxo-3-pyrrolidinyl)methyl]-4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-1-piperazinecarboxamide
• Synonyms: N-[(1-benzyl-5-oxo-3-pyrrolidinyl)methyl]-4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-1-piperazinecarboxamide
• CAS NO: 156640-14-1
• Molecular Formula: C30H32Cl2N4O2
• Molecular Weight: 551.50668
• Mol File: 156640-14-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[(1-benzyl-5-oxo-3-pyrrolidinyl)methyl]-4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-1-piperazinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(1-benzyl-5-oxo-3-pyrrolidinyl)methyl]-4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-1-piperazinecarboxamide(156640-14-1)
• EPA Substance Registry System: N-[(1-benzyl-5-oxo-3-pyrrolidinyl)methyl]-4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-1-piperazinecarboxamide(156640-14-1)

Safety Data

• Hazardous Substances Data: 156640-14-1(Hazardous Substances Data)

Upstream product

• 156640-09-4 1-(2,3'-dichlorobenzhydryl)piperazine 
• 156640-08-3 1-ethoxycarbonyl-4-(2,3'-dichlorobenzhydryl)piperazine 
• 126517-26-8 2,3'-Dichlorobenzhydryl Chloride 
• 97205-34-0 1-Benzyl-4-aminomethyl-pyrrolidin-2-one 
• 156640-11-8 <4-(2,3'-dichlorobenzhydryl)piperazin-1-yl>carbonyl chloride 

Relevant articles and documents

POTENTIAL NOOTROPIC AGENTS: SYNTHESIS OF SOME 1,4-DISUBSTITUTED 2-OXOPYRROLIDINES AND SOME RELATED COMPOUNDS

4-(Aminomethyl)-1-benzyl-2-oxopyrrolidine (VI) was transformed by treatment with (4-benzhydrylpiperazin-1-yl)carbonyl chlorides IIIb-IIId and with (4-methylpiperazin-1-yl)carbonyl chloride (IIIa) to the carboxamides IVa-IVd.Heating of 1-(ethoxycarbonylmethyl)-2,4-dioxopyrrolodine (XIX) in acetonitrile in the presence of water afforded XVIIIa.Treatment with ammonia led to the diamide XVIIIc, while alkaline hydrolysis of XVIIIa gave the dicarboxylic acid XVIIIb. 4-(Aminomethyl)-1-(4-methylthiobenzyl)-2-oxopyrrolidine (XII) was prepared by the reaction of 4-(methylthio)benzylamine with itaconic acid and the following sequence of reaction ...