1566426-71-8Relevant academic research and scientific papers
One-pot synthesis of quinoline derivatives using choline chloride/tin (II) chloride deep eutectic solvent as a green catalyst
Shahabi, Dana,Tavakol, Hossein
, p. 324 - 328 (2016)
In this work, various quinoline derivatives were prepared efficiently through a one-pot, three component synthesis using choline chloride/tin(II) chloride (ChCl·2SnCl2) deep eutectic solvent (DES) as a green catalyst. The procedure is free of using toxic solvents or catalyst and it could be categorized as a green method. In this procedure, aniline derivatives, aromatic aldehydes and enolizable aldehydes were mixed in the presence of DES that plays both roles of solvent and the reaction catalyst. Using this methodology, quinoline derivatives were synthesized simply at 60 °C in 2-3 h with high yields (54-97%). All products were purified by chromatography and recrystallization in ethanol. The employed DES have been recycled 4 time without important loss of its activity.
Zinc cation supported on carrageenan magnetic nanoparticles: A novel, green and efficient catalytic system for one-pot three-component synthesis of quinoline derivatives
Keshavarzipour, Fariba,Tavakol, Hossein
, (2017/07/25)
This is the first report of supporting zinc cation on ?-carrageenan/Fe3O4 magnetic nanoparticles. The structural and magnetic properties of this hybrid (Zn2 +/?-carrageenan/Fe3O4 nanoparticles) were identified using various techniques. This green and efficient catalytic system was applied in the synthesis of biologically important quinolines. The products were obtained in good to high yields (52–95%) from a one-pot reaction procedure involving aromatic aldehydes, enolizable aldehydes and aniline derivatives. Our method has many advantages such as mild reaction conditions, easy work-up, use of a reusable magnetic catalyst and high yields of products.
New pyridinium-based ionic liquid as an excellent solvent-catalyst system for the one-pot three-component synthesis of 2,3-disubstituted quinolines
Anvar, Salma,Mohammadpoor-Baltork, Iraj,Tangestaninejad, Shahram,Moghadam, Majid,Mirkhani, Valiollah,Khosropour, Ahmad Reza,Landarani Isfahani, Amir,Kia, Reza
supporting information, p. 93 - 100 (2014/04/03)
The synthesis of a variety of 2,3-disubstituted quinolines has been achieved successfully via a one-pot three-component reaction of arylamines, arylaldehydes and aliphatic aldehydes in the presence of butylpyridinium tetrachloroindate(III), [bpy][InCl4], ionic liquid as a green catalyst and solvent. Mild conditions with excellent conversions, and simple product isolation procedure are noteworthy advantages of this method. The recyclability of the ionic liquid makes this protocol environmentally benign.
