1566599-09-4

Basic information

• Product Name: Boc-D-3-pyridylalanine-O-Benzyl-trans-4-hydroxy-L-proline-2-Aminoindane-2-carboxylic acid-Phenylalanine-NMe₂
• Synonyms: Boc-D-3-pyridylalanine-O-Benzyl-trans-4-hydroxy-L-proline-2-Aminoindane-2-carboxylic acid-Phenylalanine-NMe₂
• CAS NO: 1566599-09-4
• Molecular Weight: 802.971
• Mol File: 1566599-09-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boc-D-3-pyridylalanine-O-Benzyl-trans-4-hydroxy-L-proline-2-Aminoindane-2-carboxylic acid-Phenylalanine-NMe₂(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-D-3-pyridylalanine-O-Benzyl-trans-4-hydroxy-L-proline-2-Aminoindane-2-carboxylic acid-Phenylalanine-NMe₂(1566599-09-4)
• EPA Substance Registry System: Boc-D-3-pyridylalanine-O-Benzyl-trans-4-hydroxy-L-proline-2-Aminoindane-2-carboxylic acid-Phenylalanine-NMe₂(1566599-09-4)

Safety Data

• Hazardous Substances Data: 1566599-09-4(Hazardous Substances Data)

Upstream product

• 98266-33-2 Boc-DPal 
• 1566599-74-3 Boc-2-Aminoindane-2-carboxylic acid-L-Phenylalanine-OMe 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 71066-00-7 2-((tert-butoxycarbonyl)amino)-2,3-dihydro-1H-indene-2-carboxylic acid 

Relevant articles and documents

Diastereo- and enantioselective addition of anilide-functionalized allenoates to N-acylimines catalyzed by a pyridylalanine-based peptide

A selective peptide-catalyzed addition of allenic esters to N-acylimines is reported. Tetrasubstituted allenes were achieved with up to 42:1 diastereomeric ratio and 94:6 enantiomeric ratio (up to 99:1 er after recrystallization of the major diastereomer). An exploration of the role of individual amino acids within the peptide was undertaken. The scope of the reaction was explored and revealed heightened reactivity with thioester-containing allenes. A mechanistic framework that may account for the observed reactivity is also described.