1566611-40-2Relevant academic research and scientific papers
Water promoted C-C bond cleavage: Facile synthesis of 3,3-bipyrrole derivatives from dienones and tosylmethyl isocyanide (TosMIC)
Wang, Rong,Wang, Shun-Yi,Ji, Shun-Jun
, p. 1735 - 1740 (2014/03/21)
A simple and highly efficient synthetic strategy to access 3,3-bipyrrole derivatives by the reaction of dienone derivatives with TosMIC is reported. The reaction involves a van Leusen's pyrrole synthesis followed by an unusual C-C bond cleavage in the presence of water under mild conditions.
