70332-83-1

Upstream product

• 1072-72-6 Tetrahydrothiopyran-4-one 
• 100-52-7 benzaldehyde 

Downstream Products

• 69559-21-3 4-[(4,5-Dihydro-2-thiazolyl)amino]tetrahydro-3,5-bis-(phenylmethylene)-2H-thiopyran-4-ol 
• 60516-72-5 3a,4,6,7-Tetrahydro-N,N-dimethyl-3-phenyl-7-(phenylmethylene)thiopyrano[4,3-c]pyrazole-2-(3H)-propanamine 
• 1289514-81-3 (4S,8E)-2-amino-7,8-dihydro-4-phenyl-8-(phenylmethylene)-4H,5H-thiopyrano[4,3-b]pyran-3-carbonitrile 
• 61448-59-7 7-(Z)-benzylidene-3-phenyl-2-propyl-2,3,3a,4,6,7-hexahydro-thiopyrano[4,3-c]pyrazole 
• 83319-86-2 7-(Z)-benzylidene-3-phenyl-1-propyl-1,4,6,7-tetrahydro-thiopyrano[4,3-c]pyrazole 
• 83319-71-5 2-{3-Phenyl-7-[1-phenyl-meth-(Z)-ylidene]-3a,4,6,7-tetrahydro-3H-thiopyrano[4,3-c]pyrazol-2-yl}-ethanol 
• 62040-86-2 2-[3-(4-Methyl-piperazin-1-yl)-propyl]-3-phenyl-7-[1-phenyl-meth-(Z)-ylidene]-2,3,3a,4,6,7-hexahydro-thiopyrano[4,3-c]pyrazole 
• 70332-84-2 1-Oxo-3,5-bis-[1-phenyl-meth-(Z)-ylidene]-tetrahydro-1λ⁴-thiopyran-4-one 
• 61448-76-8 3-Phenyl-7-[1-phenyl-meth-(Z)-ylidene]-2,3,3a,4,6,7-hexahydro-thiopyrano[4,3-c]pyrazole 
• 1566611-40-2 bis((4-phenyl-1H-pyrrol-3-yl)methyl)sulfane 
• 83319-76-0 2-(4-chlorobenzoyl)-2,3,3a,4,6,7-hexahydro-3-phenyl-7-(phenylmethylene)thiopyrano[4,3-c]pyrazole 5,5-dioxide 
• 83319-75-9 2-benzoyl-2,3,4,4a,4,6,7-hexahydro-3-phenyl-7-(phenylmethylene)thiopyrano[4,3-c]pyrazole 5,5-dioxide 

Relevant academic research and scientific papers

A convenient one-pot synthesis of thiopyrano[4,3-b]pyran derivatives under LiOH·H2O/EtOH/ultrasonic conditions

Various derivatives of thiopyrano[4,3-b]pyran structure are synthesized via a multicomponent procedure starting from tetrahydro-4H-thiopyran-4-one, aromatic aldehydes, and malononitrile. Reactions take place by the use of catalytic quantities of LiOH·Hsu

Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis

The invention belongs to the technical field of medicines, and particularly relates to application of a specific monocarbonyl curcumin analogue in preparation of a medicine for preventing and treating periodontitis. Experiments prove that the monocarbonyl curcumin analogues not only can play a better anti-oxidation protection role by activating an Nrf2/HO-1 signal channel, but also can play an anti-inflammatory role by inhibiting release of inflammatory factors TNF alpha and IL1-beta, so that the monocarbonyl curcumin analogues have a remarkable prevention and treatment effect on rat periodontitis, have good potential value and significance for prevention and treatment of periodontitis, and have a good research and development prospect.