156700-92-4Relevant academic research and scientific papers
Asymmetric Synthesis of the Volatile Anesthetic 1,2,2,2-Tetrafluoroethyl Chlorofluoromethyl Ether Using a Stereospecific Decarboxylation of Unusual Stereochemical Outcome
Rozov, Leonid A.,Rafalko, Patrice W.,Evans, Suzanne M.,Brockunier, Linda,Ramig, Keith
, p. 1319 - 1325 (1995)
Acid 1 is optically resolved by diastereomeric amide formation/chromatography/hydrolysis.Decarboxylaion of the enantiomers of acid 1 gives the enantiomers of ether 2 with a very high degree of stereospecificity.The absolute configurations of both the star
